3 FDA Authorized and Approved COVID-19 Vaccine Types

The spread of newest COVID-19 variant, the Delta, is currently making quite a spike of cases around the world. Luckily, there are plenty of reports about COVID-19 vaccine effectiveness, as time goes by. However, there are many different types of vaccine for this specific virus, so how they differ between each other?

Keeping up with the medical and technology advances regarding this topic might sound like a daunting task, but it can help you to filter the flood of correct and wrong information that come from various directions. Besides, it is important if you are planning to travel in near future, so you are able to at least keep yourself and people around you safe by getting educated about the vaccine that you have or are going to receive.

Johnson & Johnson

Various types of COVID-19 vaccine can be differentiated by how they work. Johnson & Johnson is classified as virus vector or carrier vaccine. It has several advantages compared to other vaccines, as it only requires single shot and is easier to distribute in refrigerator temperature instead of freezer temperature.

Working mechanism

Deemed as one of the best covid vaccine, Johnson & Johnson work with carrier approach. It instructs your body cells to create spike protein of SARS CoV-2. Spike protein contains code and cells that cannot make human sick, but when the code gets inside your cells, it will be able to generate spike protein to drill your immune system to create memory cells and antibodies in case it has to fight against the real SARS-CoV-2.

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Johnson & Johnson is reported to have 86% efficacy to fight severe disease and 72% efficacy in general. This COVID-19 vaccine also has been reported to be effective to fight Delta variant, with only a little decrease in potency compared to the alpha and beta variant.

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Pfizer-BioNTech is the first amongst other coronavirus vaccines to receive authorization from FDA. It is deemed to be approved after going under clinical trial with positive results – showing effectiveness as high as 95% to prevent the virus.

Currently, Pfizer as the manufacturing and distributing company is looking for authorization from FDA for third dose. That being said, the CDC and FDA have stated that fully vaccinated person wouldn’t need COVID-19 vaccine shot booster. Still, Pfizer-BioNTech is going to undergone another clinical trial to test its efficacy against Delta variant.

Working mechanism

Pfizer-BioNTech is a covid-19 vaccine that uses mRNA (messenger RNA) technology, which is relatively new. It doesn’t work by deactivating the disease or weakened it. Instead, it contains a tiny portion of SARS CoV-2 virus genetic code, and makes your body host it. Thus, your cells will create its spike protein’s copies in the host cells. Once the host cells are penetrated and infected, your body will stimulate antibodies and memory cells as immune response, which will be used if you are infected by the true virus.


This vaccine is reported to have 95% efficacy to prevent COVID-19 virus. Regarding the newest variant, there are two studies conducted in England that showed Pfizer-BioNTech has 88% effectiveness to combat Delta variant after two doses or full vaccination and 96% effective for hospitalized persons.


Moderna is the second COVID-19 vaccine to receive authorization of use and administration from FDA, only about one week after the authorization upon Pfizer-BioNTech. Using the similar mechanism to the earlier approved vaccine which is mRNA technology, both have more or less similar amount of efficacy against the virus.

However, Moderna has two primary benefits against the other mRNA vaccine. It can be distributed through long shipping period (30 days), given that it is stored in freezer temperature. This makes the specific corona vaccine easier to store and distribute.

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Working mechanism

As mRNA type of vaccine, the shot of Moderna will send instructions to your body cells to create spike protein. The spike protein is going to be used to train your immune system, so it can recognize and oppose the actual SARS CoV-2 virus that contains similar spike protein.


Moderna is reported to have 94.1% to prevent infection if you have no prior history of being infected by COVID-19 virus. Its effectiveness against the Delta variant requires further research, but several researchers and experts said that it may have similar amount of efficacy as Pfizer, due to both being mRNA type of vaccine.
Getting vaccinated fully and properly is a must if you have to travel. Please make sure that you have followed the international travel recommendations from CDC. It’s best to wait until you’re already fully vaccinated until your next trip.

However, if you have received your full dozen of COVID-19 vaccine, there’s a better reassurance of your health and safety. You may book for an airplane ticket and hotel reservation at Airpaz.com, which provides safe and secure service during this unfortunate climate.


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